‘We have become pleased to advance ALN-AS1 as a fresh Development Candidate inside our 'Alnylam 5×15' pipeline, with the purpose of filing an IND in 2014. Our fresh pre-clinical data show that subcutaneous administration of ALN-AS1 results in full suppression of the toxic heme biosynthesis intermediates that trigger the symptoms and pathology of AIP,’ said Rachel Meyers, Ph.D., Vice President of Research and RNAi Lead Advancement at Alnylam.4 percent of Dutch doctors providing a lot more than just medical advice A recent survey amongst Dutch man doctors found 4 % experienced sexual contact with a number of patients. The survey carried out by sexologist Peter Leusink in 2002, of about a thousand family doctors was published in the Dutch Journal of Medication on Saturday and covered prominently in the dutch nationwide media. Citing Leusink’s outcomes, the Algemeen Dagblad said 4 daily.3 % of male doctors surveyed and 0.8 % of female doctors had admitted sexual connection with patients, in most cases with one patient, however in a third of cases with several. ‘ We are not just talking about one-off incidents but a structural problem which must be directly addressed.